Primarily concerning the digital health services and an interaction with the online pharmacies that propels the growth of the digital pharmacy market. With a large population that increasingly prefers online shopping, this digital transformation is propelling the demand for online pharmacies. Based on regional analysis, the online pharmacy market in North America accounted for second largest revenue share in 2022.
Major Players
In light of the explosive growth of online pharmacies, a more comprehensive understanding of IOPs is urgently needed. Therefore, the current scoping review aims to offer a broad overview of this literature, with attention primarily devoted to research themes and subthemes. More specifically, this scoping review identifies key themes arising in the IOP literature, main gaps where additional research is necessary and directions for future research. The alternative hypothesis is that COVID-19 engendered a change in the behaviour of cryptomarkets participants. COVID-19 impacted upon many national economies and led to many people losing their jobs (Barua, 2020).
Illicit Online Pharmacies: A Scoping Review

In addition, government healthcare initiatives will likely boost online pharmacies as consumers improve their health, leading to higher spending on over-the-counter drugs during the forecast period. Similarly, the growth of the online pharmacy market in Europe is highly affected by the increasing internet penetration, the implementation of e-prescribing norms, the improvement of virtual payments, and the rapidly aging population. Asia Pacific is poised to experience the fastest growth in the online pharmacy market, driven by the rapidly expanding middle-class population, increasing disposable income, and improving internet infrastructure. The region’s large and diverse population presents significant opportunities for online pharmacies to tap into new customer segments.

The rising adoption of telemedicine and digital health technologies enhances the synergy between online pharmacies and healthcare providers, facilitating better patient engagement and medication management. The COVID-19 pandemic accelerated the shift toward online healthcare solutions, highlighting the importance of remote services. The increasing availability of mobile apps for prescription refills and consultations also enhances the consumer experience. The OTC products sub-segment held more than 70% of the market in 2024 and is expected to grow significantly during the forecast period.
Otherwise known as ‘cryptomarkets’, these allow goods and services to be exchanged between parties who use digital currencies (e.g. bitcoin) and digital encryption software (e.g. Tor) to conceal their identities (3). The growth of social media has also seen online fora and mobile ‘apps’ emerge, where drugs are discussed, advertised and sometimes sold. However, little research has gone beyond theorizing the market changes that could possibly affect drug use and sales and documenting if illegal purchases of drugs have indeed occurred. In addition to cost savings and convenience, patients purchase from IOPs to self-medicate and overcome their lack of a prescription, healthcare providers’ refusal to prescribe, dissatisfaction with providers or embarrassment regarding their condition 10.
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Owing to the various government initiatives, the online mode of payment is projected to increase during the forecast period. Cash on delivery is popular among consumers in Eastern Europe, and credit/debit card is popular in EU5 except in a few countries where payment wallets such as iDeal are popular. The medications category holds the largest share, of 55%, in 2024, on account of the surge in the sales of OTC as well as prescription medications.
Drugs Market Trends
North America contributed 42.34% of global revenue in 2024, making it the largest regional market. Some focus on underserved therapeutic areas such as sexual health, pairing teleconsults with discreet shipping. Others bundle at-home diagnostics with same-day prescription delivery, positioning themselves as 360-degree condition-management portals. These asset-light models can pivot quickly, but payer alignment remains a critical hurdle without proprietary PBM backing. Cross-device cart sync ensures a price check on a phone can end in payment on a laptop without data loss, paring drop-offs.
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Drugs are substances other than food, derived from natural, synthetic, or semisynthetic sources, containing active pharmaceutical ingredients (API) and excipients, to achieve their pharmacological activity in the body. They are utilized in mild to severe illness conditions to relieve the pain or issues in patients suffering from different normal or abnormal symptoms. Globally, the growing prevalence of chronic diseases, along with novel developments in drug delivery systems, biologics, personalized medicine, and AI-aided therapeutics, is enhancing the treatment outcomes. Also, majorly relying on patient-targeted solutions, like home-based care and optimized drug delivery technologies, is contributing to growth factors in the drugs market expansion. This path will be of great importance might we face similar health emergencies in the years to come.
Brazil’s Crackdown On Criminal Links To Fuel Supply Chain Nets $220 Million In Assets
Moreover, future research should employ random sampling techniques rather than the convenience samples pervasive in the prior literature to enhance generalizability. Although most research has studied the IOP phenomenon overall, some studies investigate IOPs in relation to a particular medication or drug category (e.g., fentanyl or psychiatric drugs). Drug-specific studies have become a strong component of IOP research since 2012, as shown in Figure 5. IOP studies related to a medication or therapeutic category were most common in the patient risk cluster (54.5%), followed by the marketing and supply chain cluster (46.2%).
- OTC products, though smaller at 28.0%, are forecast to rise at an 18.12% CAGR as self-care culture spreads and same-day courier networks expand.
- A lack of governance norms and strict, time-consuming regulatory procedures are other challenges restricting revenue growth of the market.
- This enables vendors to claim to have shipped the illicit drugs when, in fact, they have not.
- Additionally, natural language processing enables platforms to interpret unstructured doctors notes and convert them into digital prescriptions.
- For instance, as per a warning issued by the FDA in 2020, some online pharmacies were caught to be engaged in illegal activity and violating the U.S.
Which Segment By Drug Type Accounted For The Major Share Of The EPharmacy Market In 2024?
- Studies of IOPs, in general, were most common in the healthcare provider (75%), public health and society (68.7%) and policy and regulation clusters (57.1%).
- According to the Index, the online purchasing of synthetic drugs may suggest the existence of an established cyber environment, which implies a heightened risk of cyber-dependent criminality.
- Grapes and baby bottles are the calling cards for codeine-containing cough syrup, or lean.
- Desktop sessions held a 55.23% share of the E-pharmacy market size in 2024 because first-time account creation and insurance uploads are easier on larger screens.
65% of the transactions amongst our sample were received without any issue, while a further 6% were received, but were impacted by a particular issue (for example, the package did not contain the right quantity of the drug). After all the data collection and validation our team does a final level of quality check and quality assurance to get rid of any unwanted or undesired mistakes. This might include but not limited to getting rid of the any typos, duplication of numbers or missing of any important information.
Virtual Markets — Changing The Dynamics Of How Drugs Are Bought And Sold

This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies.
Online Pharmacy – United States

A substantial number of studies published in high quality peer-reviewed journals have used mortality rate to account for the severity of the pandemic in their publication (see for example Ammar et al., 2020; Le & Nguyen, 2021; Rahman et al., 2020). Ammar et al. (2020) find a correlation between the level of distancing measures and the number of COVID-19 related deaths, without being able to identify a causal relationship. Le and Nguyen (2021) in their paper published in Economics & Human Biology claim that “given the shortage of testing capability in the early days, mortality rate is currently the best measure of the severity of the pandemic”. As we want to test the impact of Covid-19 and the related social distancing measures on cryptomarkets, we consider mortality rate as the best measure of the impact of the pandemic.